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Impurezas de degradação
Leite, Flavio
Palavras-chave: Impurity, degradation impurity, composed isolation.
Resumo: Nowadays analytical chemistry scientists must face the challenge of isolating compounds that are present in minor quantities in other compounds. Considering that the target substances can be reaction byproducts, impurities or degradation compounds which can present complex carbonic chains and functional groups, sophisticated identification and separation techniques are required. Every synthesized or extracted product presents an equilibrium of chemical reactions that keep molecular structures stable to certain conditions like temperature, pressure, humidity, salinity, pH, viscosity, solubility, speed, etc. When this equilibrium is disrupted by physical or chemical agents like light, heat, oxidation, dehydration, secondary reactions may take place and, as a consequence, new structures can appear in the final product. These structures, along with reagent residues from the chemical route of production and residues of solvents, compose the IMPURITIES of the active ingredient or DEGRADATION IMPURITES.
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