Chromatographic supports and stationary phases for liquid chromatography: preparation, evolution and trends

Nazario, Carlos Eduardo D.; Lanças, Fernando M.

Palavras-chave: HPLC, chromatographic support, silica, stationary phase.

Resumo: Since the development of instrumentation for HPLC, this analytical technique has been widely employed in the separations and analysis of a large variety of compounds in different fields. In this context, research and development (R & D) area of chromatographic supports and stationary phases for HPLC have been receiving attention from researchers aiming the decrease in analysis time, increase column efficient and promote adequate selectivity. In this paper, we focused on the methods for the preparation of chromatographic supports for HPLC (especially silica-based materials) and strategies for modifying its surface in the preparation of stationary phases.

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