http://dx.doi.org/10.4322/sc.2017.009

Moduladores de fluxo para cromatografia gasosa bidimensional abrangente

Bjerk, Thiago Rodrigues; Machado, Maria Elisabete; Caramão, Elina Bastos; Tranchida, Peter Q.; Mondello, Luigi; Zini, Claudia Alcaraz

Palavras-chave: Cromatografia gasosa bidimensional abrangente, modulador de fluxo, detector de espectrometria de massas.

Resumo: Esta revisão apresenta os princípios fundamentais do funcionamento dos moduladores de fluxo em conjunto com a cromatografia gasosa bidimensional abrangente, bem como os principais modelos de moduladores de fluxo que marcam a evolução tecnológica dos mesmos. Estes moduladores apresentam grande potencial para o desenvolvimento da cromatografia bidimensional abrangente, pois apresentam baixo custo de operação, o que torna a técnica mais acessível. Além disso, é possível minimizar a perda de sensibilidade na hifenação do sistema cromatográfico com detectores de espectrometria de massas, empregando-se moduladores de baixo fluxo (< 8 mL min-1).


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