http://dx.doi.org/10.4322/sc.2016.003

 

Single drop microextraction (SDME): fundamentals and applications

Pinto, Iohana Pinto de; Pedroso, Marcio Pozzobon

Palavras-chave: samples preparation, liquid phase microextraction, chromatography, single drop.

Resumo: The classical sample preparation techniques are being replaced by miniaturized techniques due to low cost, low solvents consume and possibility of automation. The first liquid phase microextraction technique developed was the single drop microextraction (SDME) and since then new operation modes have been developed. The SDME principle is based on partition of the analytes between the sample and a small drop of an organic solvent. Theoretical principles, operation modes and recent applications of the SDME in the determination of organic compounds by chromatographic techniques are presented in this review.


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