http://dx.doi.org/10.4322/sc.2016.036

Extração em fase sólida magnética (MSPE): Fundamentos e aplicações

Silva, Amandha Kaiser da; Sobieski Neto, Eduardo; Viana, Luiz Henrique; Lanças, Fernando M.; Nazariob, Carlos Eduardo Domingues

Palavras-chave: preparo de amostra, MSPE, nanopartículas magnéticas, análise de traços.

Resumo: Diversas estratégias de preparo de amostras têm sido desenvolvidas com o objetivo de diminuir a tempo de análise e a manipulação da amostra, e maximizar a pré- concentração dos analitos em matrizes complexas. O uso da tecnologia de separação magnética tem se destacado para esta finalidade pela simplificação das etapas de preparo de amostra. Neste conceito, a extração em fase sólida magnética (MSPE) baseia-se na manipulação de nanopartículas magnéticas para promover a separação das fases. Além da simplicidade e alta eficiência de extração, a MSPE supera alguns inconvenientes da SPE e d-SPE convencional. Nesta revisão, são discutidos os conceitos e estratégias de síntese das partículas magnéticas modificadas com diversos recobrimentos (sílica, MIP, surfactantes, líquidos iônicos, grafeno e derivados) para a extração e pré-concentração dos analitos em diversas matrizes.

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