Magnetic solid phase extraction (MSPE): Fundamentals and applications

Silva, Amandha Kaiser da; Sobieski Neto, Eduardo; Viana, Luiz Henrique; Lanças, Fernando M.; Nazariob, Carlos Eduardo Domingues

Palavras-chave: sample preparation, MSPE, magnetic nanoparticles, trace analysis.

Resumo: Several sample preparation strategies have been developed in order to decrease the analysis time and sample manipulation, and to maximize the analytes preconcentration in complex matrices. The use of magnetic separation technology has been highlighted for this purpose by the simplification of the sample preparation steps. In this concept, the magnetic solid phase extraction (MSPE) is based on the manipulation of magnetic nanoparticles to promote phase separation. In addition to simplicity and high extraction efficiency, the MSPE overcomes some drawbacks of conventional SPE and d-SPE. In this review, the authors discuss the concepts and strategies to prepare magnetic particles modified with different coatings (silica, MIP, surfactants, ionic liquids, graphene and derivatives) for the extraction and preconcentration of the analytes in several matrices.

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