Problemas com o formato dos picos em cromatografia líquida
Santos Neto, Álvaro José
Palavras-chave: Asymmetry, Peak tailing, Peak fronting, Peak distortions, HPLC, Liquid chromatography.
Resumo: This edition continues discussions about peak shape problems occurring in liquid chromatography. Peak distortions like tailing, fronting, widening, and double peaks or peaks with shoulders may occur due to several reasons and this matter needs to be detailed to provide chromatographic users with background to solve these problems. Following the previous articles, this one discusses not only physical but also chemical aspects related with separation. The most common contributions to peak distortion will be briefly studied and exemplified for a better understanding, and strategies to overcome these problems will be presented as well.